Biology simulations
139 interactive Biology simulations for ages 11–18, grouped by topic.
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ATP and energy coupling – ATP hydrolysis drives endergonic reactions, the ATP–ADP cycle
Biology · Cell Biology
Three screens on ATP as the cell's energy currency. ΔG bars show ATP hydrolysis (ATP + H₂O → ADP + Pi, ΔG°′ ≈ −30.5...
Ages 15–16
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Cell types gallery – specialised cells, unicellular organisms and atypical cells
Biology · Cell Biology
Seventeen schematic drawings: sperm, egg, motor neuron, skeletal muscle fibre, red blood cell, ciliated epithelial...
Ages 15–16
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Levels of biological organization
Biology · Cell Biology
Zoom continuously from molecules up to the biosphere: molecule, organelle, cell, tissue, organ, organ system,...
Ages 15–16
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Carbohydrates and lipids – building molecules, bonds and functions
Biology · Cell Biology
Build molecules from α-glucose and β-glucose (the OH on carbon 1 below or above the ring): condensation forms 1,4...
Ages 15–16
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3D
Protein Structure in 3D – from Amino Acids to Quaternary Structure
Biology · Cell Biology
A rotatable 3D model of proteins: amino acids (amine group, carboxyl group, R group) join by peptide bonds in...
Ages 15–16
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Root-tip squash practical – stages of mitosis and mitotic index
Biology · Cell Biology
A virtual practical: hydrolyse onion root tips in hydrochloric acid, stain and squash them, then view the cells at...
Ages 15–16
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Cell cycle and mitosis
Biology · Cell Biology
The cell cycle ring runs G1 → S → G2 → M with a phase hand, three checkpoints, and a DNA-content graph; alongside...
Ages 15–16
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Cellular respiration pathway – glycolysis, link reaction, Krebs cycle, electron transport chain and fermentation
Biology · Cell Biology
Step through glycolysis in the cytoplasm, the link reaction and Krebs cycle in the mitochondrial matrix, and...
Ages 15–16
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Characteristics of Living Things – Living or Non-living and the Three Life Functions
Biology · Cell Biology
Test eight specimens – a bean seed, a virus, fire, a robot, yeast, a salt crystal, a mushroom and a dead leaf – for...
Ages 11–12
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Enzyme activity vs. temperature, pH, substrate concentration and inhibitors
Biology · Cell Biology
The enzyme (with an active site) and substrate molecules move around and collide; when a substrate molecule fits the...
Ages 15–16
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Meiosis and the origin of gamete variation
Biology · Cell Biology
Step through each phase of meiosis I and II in a cell with n pairs of homologous chromosomes. Toggle crossing over...
Ages 15–16
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Tissues under the microscope – plant and animal histology slide box
Biology · Cell Biology
A box of 20 prepared slides and a virtual microscope: meristem, parenchyma, collenchyma, sclerenchyma, xylem, phloem...
Ages 11–12
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Surface Area to Volume Ratio – Agar Cube Diffusion
Biology · Cell Biology
Virtual lab: drop pink agar blocks (made with dilute sodium hydroxide and phenolphthalein), cubes of side 0.5–3 cm...
Ages 15–16
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Diffusion across membranes and osmosis in cells
Biology · Cell Biology
On the left, small molecules diffuse through membrane pores from high to low concentration until equilibrium, with...
Ages 15–16
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Food tests – sugars, starch, protein and fats in unknown foods
Biology · Cell Biology
Run the classic food tests in a virtual lab: Benedict's reagent in a hot water bath for reducing sugars, iodine for...
Ages 15–16
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Water and macromolecules – polarity and hydrogen bonding
Biology · Cell Biology
The water mode draws polar H₂O molecules with an oxygen end carrying a partial negative charge and two hydrogen ends...
Ages 15–16
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Metabolism – following atoms through digestion, respiration and building
Biology · Cell Biology
Follow the atoms of a meal: starch, protein or fat is hydrolysed into monomers, some of the monomers are respired...
Ages 15–16
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Eukaryotic and prokaryotic cell structure
Biology · Cell Biology
Diagrams of an animal cell, a plant cell and a bacterium with organelles drawn in their correct positions. Students...
Ages 15–16
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Microscopy lab – slides, calibration, cell size and electron microscopes
Biology · Cell Biology
A virtual practical: make temporary mounts (onion epidermis with iodine, cheek cells with methylene blue, Elodea...
Ages 15–16
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Beetroot Membrane Permeability Practical – Temperature and Ethanol
Biology · Cell Biology
Cut beetroot discs, rinse them, soak them in water from 0 to 70 °C or in ethanol from 0 to 100 %, then read the...
Ages 15–16
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Cell signalling – signalling modes and signal transduction pathways
Biology · Cell Biology
Compare direct contact, paracrine and endocrine signalling and quorum sensing in bacteria: drag a target cell nearer...
Ages 15–16
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Membrane transport – diffusion, channels and pumps
Biology · Cell Biology
Add substances on either side of the cell membrane, then insert channel proteins, carriers and pumps to see how they...
Ages 15–16
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Community How Neurons Send Signals: Action Potentials and Synapses
Biology · Cell Biology
A chain of three neurons passes electrical signals along axons and chemical signals across synapses. A live graph...
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Community Phosphorus cycle and fertiliser runoff
Biology · Cell Biology
A box-and-arrow model of the phosphorus cycle through rocks, soil, plants, animals, a lake, the ocean and sediments....
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Viral replication – lytic and lysogenic cycles
Biology · Microbiology & Viruses
A phage attaches to a bacterium and injects its DNA, the host cell synthesizes viral DNA and coat protein, assembles...
Ages 15–16
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Fungi explorer – hyphae, spores, yeast and the roles of fungi
Biology · Microbiology & Viruses
Look at bread mould, Penicillium, yeast and mushroom gills under a virtual microscope, follow the mushroom life...
Ages 11–12
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Fermentation – lactic acid and ethanol pathways
Biology · Microbiology & Viruses
Incubate a batch culture with microorganisms: choose the strain, temperature, initial sugar level and whether oxygen...
Ages 15–16
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Microbe gallery – bacteria, archaea, protists and fungi
Biology · Microbiology & Viruses
Twelve microbes with animations of how each one feeds, moves and reproduces: a bacterium, an archaeon, a...
Ages 11–12
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Bacterial population growth curve
Biology · Microbiology & Viruses
A bacterial population in a culture flask grows following N = N₀·2^(t/g); a graph of log N against time plots itself...
Ages 15–16
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Bacteria in food – the temperature danger zone
Biology · Microbiology & Viruses
How long can cooked food sit out before it's unsafe? Pick a bacterium (Salmonella, Staphylococcus aureus, or...
Ages 16–17
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Zones of inhibition – antiseptics and antibiotics on bacteria
Biology · Microbiology & Viruses
A paper-disc assay on an agar plate: perform or skip each step of aseptic technique (a skipped step lets contaminant...
Ages 15–16
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Biotech bench – transformation, restriction digest and gel
Biology · Biotechnology
Gene-technology practicals on one virtual bench. Transform E. coli with a plasmid carrying an ampicillin-resistance...
Ages 17–18
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CRISPR-Cas9 gene editing – find, cut and repair
Biology · Biotechnology
A textbook-style model of gene editing. Load one of four guide RNAs into Cas9 and watch it search made-up DNA: it...
Ages 17–18
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Biotechnology – cell, enzyme, and microbial technologies
Biology · Biotechnology
Three biotechnology topics in one simulation, selected with the topic parameter. Cell technology: plant tissue...
Ages 15–16
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Industrial enzymes – Michaelis–Menten kinetics and immobilized enzymes
Biology · Biotechnology
Pick a real-world application – lactase for lactose-free milk, pectinase for clarifying fruit juice, protease in...
Ages 15–16
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Cloning and transgenic organisms – a virtual lab
Biology · Biotechnology
Four step-by-step procedures on a virtual bench. Split a cattle embryo into 2–4 parts and transfer them into...
Ages 15–16
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Plant tissue culture – micropropagation
Biology · Biotechnology
A leaf tissue explant is cultured on a medium containing auxin and cytokinin. Drag the two hormone concentrations to...
Ages 15–16
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PCR – amplifying DNA by thermal cycling
Biology · Biotechnology
Each PCR cycle consists of denaturation at 95 °C, primer annealing, and extension at 72 °C, doubling the number of...
Ages 17–18
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DNA extraction practical – strawberry, banana, onion or cheek cells
Biology · Biotechnology
Virtual DNA extraction: mash strawberry, banana or onion tissue (or collect cheek cells), add detergent and salt,...
Ages 17–18
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Wastewater treatment by microorganisms – activated sludge tank
Biology · Biotechnology
Wastewater rich in organic matter (high BOD) flows into a tank, where aerobic bacteria feed on the organic matter...
Ages 15–16
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Leaf structure and stomatal density – leaf cross-section and a nail-varnish leaf cast
Biology · Plant Physiology
Three screens on the leaf as the organ of photosynthesis: a leaf cross-section with cuticle, epidermis, palisade and...
Ages 16–17
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Transport in plants – root uptake, xylem and phloem
Biology · Plant Physiology
Follow water from the soil into root hair cells, across the cortex and endodermis to the xylem, and up to the leaves...
Ages 16–17
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Plant anatomy – T.S. of dicot and monocot roots and stems
Biology · Plant Physiology
A virtual practical: cut thin transverse sections of sunflower and maize stems and roots, stain them with safranin,...
Ages 16–17
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Morphology of Flowering Plants: Roots, Stems and Leaves
Biology · Plant Physiology
Explore real flowering plants drawn as labelled diagrams: tap and fibrous roots and their modifications (storage,...
Ages 11–12
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Respirometer – oxygen uptake of germinating seeds
Biology · Plant Physiology
Three respirometer tubes in a water bath: germinating seeds, dry seeds plus glass beads, and glass beads only...
Ages 16–17
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Plant growth hormones and insect metamorphosis
Biology · Plant Physiology
In plant mode, treat a seedling with a hormone at a concentration you drag along the scale: at low concentrations...
Ages 16–17
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Plant groups and alternation of generations – life-cycle wheel
Biology · Plant Physiology
Compare algae, mosses, ferns, conifers and flowering plants by vascular tissue, roots, seeds, flowers and fruit on...
Ages 16–17
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Light-dependent reactions and the Calvin cycle – electron transport, ATP synthase, RuBP/GP/TP and the ¹⁴C tracer experiment
Biology · Plant Physiology
A thylakoid membrane with photosystems II and I, photolysis of water, an electron transport chain that pumps H⁺ into...
Ages 16–17
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Hill Reaction Practical – DCPIP and Isolated Chloroplasts
Biology · Plant Physiology
Blend leaves in cold isolation medium, filter and centrifuge to get chloroplasts, then add blue DCPIP and read the...
Ages 16–17
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Absorption and action spectra of photosynthesis – pigments, Engelmann's experiment and chromatography
Biology · Plant Physiology
Four screens on photosynthetic pigments: shine light of single wavelengths from 400 to 700 nm at equal photon flux...
Ages 16–17
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C3, C4 and CAM Photosynthesis and Photorespiration
Biology · Plant Physiology
Compare the net photosynthesis of wheat (C3) and maize (C4) as you change light, CO₂ and temperature, and watch...
Ages 16–17
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Photosynthesis rate – light, CO₂, temperature and the compensation point
Biology · Plant Physiology
A sprig of pondweed under a lamp releases O₂ bubbles faster or slower with light intensity, CO₂ concentration and...
Ages 16–17
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Photosynthesis practicals – starch test on leaves and hydrogencarbonate indicator
Biology · Plant Physiology
Two virtual practicals on photosynthesis and gas exchange. Destarch a plant for 48 h in the dark, light variegated...
Ages 12–13
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Transpiration and stomatal control
Biology · Plant Physiology
Adjust light, air humidity, wind and soil moisture, then watch the stomata open or close, the transpiration rate...
Ages 16–17
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Flowering plant reproduction lab – dissection, pollination, dispersal and germination
Biology · Plant Physiology
A virtual lab on reproduction in flowering plants. Dissect an insect-pollinated flower, a wind-pollinated flower or...
Ages 16–17
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Hydroponic vegetables – mineral nutrition and the law of the minimum
Biology · Plant Physiology
Mix a nutrient solution for hydroponic vegetables by adjusting N, P, K concentrations and pH. The plant shows the...
Ages 16–17
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Choice chamber – taxis and kinesis in woodlice, maggots and fruit flies
Biology · Human & Animal Physiology
A virtual behaviour practical: put woodlice, blowfly maggots or fruit flies in a choice chamber or a T-maze with...
Ages 16–17
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Homeostasis – blood glucose and body temperature
Biology · Human & Animal Physiology
Eat a meal and watch blood glucose change minute by minute. In a healthy person, glucose entering the blood raises...
Ages 16–17
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Human ovulation cycle and plant double fertilization
Biology · Human & Animal Physiology
A 28-day cycle clock runs through in about ten seconds: four curves for FSH, LH, estrogen, and progesterone change...
Ages 16–17
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Cardiac cycle – pressure, heart valves, ECG and control of heart rate
Biology · Human & Animal Physiology
A four-chamber heart beats in slow motion: the sinoatrial node (SAN) fires, the wave spreads over the atria, is...
Ages 16–17
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Breathing mechanics, spirometry and gas exchange
Biology · Human & Animal Physiology
The diaphragm and intercostal muscles change the volume of the thorax, so the pressure in the lungs falls or rises...
Ages 16–17
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Muscle contraction – the sliding filament model
Biology · Human & Animal Physiology
Watch a sarcomere contract by the sliding filament model: a nerve impulse reaches the neuromuscular junction, the...
Ages 16–17
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Neuron resting and action potential
Biology · Human & Animal Physiology
A cross-section of the neuron membrane shows Na⁺ and K⁺ ions on both sides, Na⁺ channels, K⁺ channels and the Na⁺/K⁺...
Ages 16–17
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Nervous control of heart rate and breathing – medulla, baroreceptors, chemoreceptors and the nervous system
Biology · Human & Animal Physiology
The medulla receives impulses from baroreceptors in the carotid sinus and aortic arch and from chemoreceptors in the...
Ages 16–17
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Oxygen Dissociation Curve – Bohr Shift, Fetal Haemoglobin and Myoglobin
Biology · Human & Animal Physiology
Plot the percentage saturation of haemoglobin against pO₂ and read how much oxygen is unloaded between the lungs and...
Ages 16–17
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Digestive system journey – enzymes, bile and absorption by villi
Biology · Human & Animal Physiology
Follow a meal from the mouth through the stomach and small intestine to the large intestine: mechanical digestion by...
Ages 16–17
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Endocrine system – glands, hormones and feedback loops
Biology · Human & Animal Physiology
An endocrine map: tap the hypothalamus, pituitary, thyroid, adrenal glands, pancreas, ovaries or testes to see their...
Ages 16–17
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The Eye and the Ear – Accommodation, Defects and Hearing
Biology · Human & Animal Physiology
A ray model of the eye: move the object near or far and watch the ciliary muscle, suspensory ligaments and lens...
Ages 16–17
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Virtual dissection – heart, lungs, fish gills and a frog model
Biology · Human & Animal Physiology
A virtual dissection lab with textbook-style drawings. Complete a risk assessment, then cut a mammalian heart to...
Ages 16–17
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Neuron – action potential and nerve impulse conduction
Biology · Human & Animal Physiology
Stimulate a neuron and watch the nerve impulse travel along the axon. Drag the circle to choose an observation...
Ages 16–17
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Gametogenesis – spermatogenesis and oogenesis side by side
Biology · Human & Animal Physiology
A side-by-side timeline of spermatogenesis and oogenesis: spermatogonium, primary and secondary spermatocytes,...
Ages 16–17
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Human Growth and Puberty – Life Stages, Growth Spurt and Growth Charts
Biology · Human & Animal Physiology
A timeline of life stages from zygote to old age with median height, mass and growth-velocity curves for girls and...
Ages 16–17
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Comparative animal physiology – organ systems from Hydra to mammals
Biology · Human & Animal Physiology
Compare two animals side by side, one organ system at a time: gas exchange, circulation (open or closed, two-,...
Ages 16–17
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Kidney, nephron and ADH – osmoregulation
Biology · Human & Animal Physiology
A nephron filters blood in the glomerulus, reabsorbs useful substances in the proximal convoluted tubule, builds a...
Ages 16–17
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Blood components, clotting and blood groups – smear, cell count, transfusion, tissue fluid
Biology · Human & Animal Physiology
Six screens on blood. Smear: tap red cells, the five kinds of white cell, platelets and plasma to see their...
Ages 13–14
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Reaction time – the ruler drop test
Biology · Human & Animal Physiology
Measure reaction time with the ruler drop test. Test yourself: the ruler is released at a random moment and you...
Ages 16–17
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Human reproduction – fertilisation, pregnancy and the placenta
Biology · Human & Animal Physiology
Labelled diagrams of the female and male reproductive systems with a naming quiz, a timeline from fertilisation in...
Ages 16–17
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Single and double circulation
Biology · Human & Animal Physiology
Compare the single circulatory system of fish side by side with the double circulatory system of mammals: blood...
Ages 16–17
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Brain regions, brain mapping and plasticity – cortex, cerebellum, medulla, homunculus and LTP
Biology · Human & Animal Physiology
Tap a schematic brain, seen from the side or cut down the middle, to find the cerebral cortex areas (motor,...
Ages 16–17
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Chemical synapse – transmission, summation and the effects of drugs
Biology · Human & Animal Physiology
Follow an impulse across a chemical synapse: an action potential reaches the presynaptic knob, Ca²⁺ channels open,...
Ages 16–17
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Skeleton, joints and antagonistic muscles – elbow lever and range of motion
Biology · Human & Animal Physiology
Tap the bones of a human skeleton to see how they support the body, protect organs, allow movement and make blood...
Ages 13–14
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Non-communicable diseases – lifestyle risk, coronary heart disease and epidemiology
Biology · Health & Disease
Four linked screens on non-communicable diseases: a 10-year energy-balance and risk model (BMI, blood pressure, type...
Ages 16–17
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Communicable diseases – pathogen casebook, spread and plant disease
Biology · Health & Disease
A casebook of 12 pathogens by type: viruses (measles, HIV, tobacco mosaic virus), bacteria (Salmonella, gonorrhoea,...
Ages 16–17
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Applied biology – mineral nutrition, human epidemics, and food safety
Biology · Health & Disease
Three applied-biology topics in one simulation, selected with the topic parameter. Mineral nutrition: choose the...
Ages 16–17
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Immune Response and Vaccination – Primary vs Secondary Response
Biology · Health & Disease
A pathogen enters the body: phagocytes destroy some of it, B lymphocytes are activated, secrete antibodies and leave...
Ages 16–17
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Immune disorders – allergy, autoimmunity and HIV/AIDS
Biology · Health & Disease
Three immune disorders in one simulation. Allergy: a first contact with pollen, dust mites, peanut or bee venom...
Ages 16–17
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Disease spread and herd immunity (SIR model)
Biology · Health & Disease
The SIR model divides a community into susceptible, infected, and recovered groups. Choose a disease (seasonal flu,...
Ages 16–17
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Monoclonal antibodies – hybridomas, ELISA and HIV testing
Biology · Health & Disease
A step-by-step virtual lab: immunise a mouse, collect B cells, fuse them with myeloma cells using PEG, select...
Ages 15–16
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Adaptive immunity – T cells, B cells and clonal selection
Biology · Health & Disease
Step by step: a macrophage presents antigen on MHC, the helper T cell with a complementary receptor is activated,...
Ages 16–17
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Innate immunity – barriers, inflammation and phagocytes
Biology · Health & Disease
A tissue model at a wound: mast cells release histamine, blood vessels widen and become leaky, neutrophils and then...
Ages 16–17
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Antibiotic Resistance – Why You Should Finish the Course
Biology · Health & Disease
A population of disease-causing bacteria already contains a few resistance mutations. Set the antibiotic dose, the...
Ages 15–16
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Variation lab – continuous vs discontinuous, genes vs environment
Biology · Genetics
A virtual practical on variation: measure height and hand span in a simulated year group (continuous variation:...
Ages 17–18
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Gene expression – transcription, translation and regulation
Biology · Genetics
Place transcription factors, RNA polymerase, ribosomes and an mRNA-degrading enzyme on a stretch of DNA carrying...
Ages 17–18
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3D
DNA and RNA Structure in 3D – from Nucleotide to Nucleosome
Biology · Genetics
A rotatable 3D model of DNA: nucleotides (phosphate, sugar, base) join by phosphodiester bonds into 5′→3′ strands,...
Ages 17–18
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Sex determination and X-linked inheritance – Punnett squares and pedigrees
Biology · Genetics
Three screens on sex chromosomes: an XX × XY Punnett square with simulated families; X-linked crosses for...
Ages 17–18
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Gene mutation and its effect on the polypeptide
Biology · Genetics
Edit one nucleotide on the template strand: substitution, insertion or deletion. The simulation re-runs...
Ages 17–18
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Hardy–Weinberg equilibrium, selection and genetic drift
Biology · Genetics
A randomly mating population with two alleles A and a: genotype frequencies p², 2pq and q² are calculated and...
Ages 17–18
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Gene linkage – crossing over and genetic mapping
Biology · Genetics
Two genes sit on the same chromosome: drag the distance between them to change the recombination frequency and watch...
Ages 17–18
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Karyotypes and non-disjunction – building a human karyogram
Biology · Genetics
Build a karyogram from a cell in metaphase: drag 46 chromosomes into pairs by length, centromere position and...
Ages 17–18
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Dihybrid cross: independent assortment, gene linkage and crossing over
Biology · Genetics
A two-gene Punnett square shows each parent's gametes and their frequencies, cells colour-coded by phenotype, and...
Ages 17–18
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DNA Replication – the Replication Fork and the Meselson–Stahl Experiment
Biology · Genetics
An animated replication fork: helicase unwinds the DNA, primase lays RNA primers, DNA polymerase III extends new...
Ages 17–18
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Transcription, translation and point mutations
Biology · Genetics
From a gene's template strand, RNA polymerase builds mRNA one nucleotide at a time by base-pairing (A–U, T–A, G–C,...
Ages 17–18
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Beyond Mendel – incomplete dominance, codominance, epistasis and the chi-squared test
Biology · Genetics
A cross simulator for nine inheritance patterns: complete and incomplete dominance, codominance, multiple alleles...
Ages 17–18
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Evidence for evolution – anatomy, embryos, fossils and molecules
Biology · Evolution
An evidence lab with four stations: colour the homologous bones of the pentadactyl limbs of a human, a bat, a whale...
Ages 17–18
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Cladograms and phylogenetic trees – build them from characters or sequences
Biology · Evolution
Build a cladogram from a table of shared derived characters rooted with an outgroup, or from aligned DNA and protein...
Ages 17–18
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Natural selection – rabbit population, mutations, wolves and food
Biology · Evolution
A rabbit population breeds over many generations: each rabbit carries two alleles of every gene (fur colour, ear...
Ages 17–18
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Natural selection – changing allele frequency (peppered moth)
Biology · Evolution
A moth population rests on tree trunks: genotypes AA and Aa give dark wings, aa gives light wings, and each genotype...
Ages 17–18
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Speciation – allopatric and sympatric (polyploidy), reproductive isolation and the species concept
Biology · Evolution
A population of mice is split in two by a geographic barrier (a river, a mountain range or the sea). The two sides...
Ages 17–18
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Fossils and dating – rock-strata dig, index fossils and radiometric dating
Biology · Evolution
Excavate two rock sequences layer by layer, record which fossils appear and disappear, and use the law of...
Ages 17–18
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Lamarck vs Darwin – two theories of evolution tested
Biology · Evolution
Two giraffe herds evolve side by side from the same short-necked ancestors. Under Lamarck's rules every giraffe...
Ages 17–18
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Specimen spotting gallery – identify and classify organisms
Biology · Evolution
A virtual spotting practical with 32 drawn specimens: bacteria, Oscillatoria, Spirogyra, Rhizopus, yeast, mushroom,...
Ages 11–12
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Drought and finch beak depth – selection on a quantitative trait, R = h²S
Biology · Evolution
A population of ground finches varies continuously in beak depth, and part of that variation is inherited...
Ages 17–18
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Origin of life – Miller–Urey experiment, spontaneous generation and protocells
Biology · Evolution
Four screens on the origin of life. Spontaneous generation: repeat Redi's meat jars, Needham's and Spallanzani's...
Ages 17–18
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Endosymbiosis and genome evolution
Biology · Evolution
Three screens on how eukaryotic cells and genomes became more complex. Endosymbiosis: along a timeline, a host cell...
Ages 17–18
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Animal kingdom – body plans and classification of phyla
Biology · Evolution
A key based on body plan: level of organisation, symmetry, germ layers, body cavity, notochord and segmentation lead...
Ages 11–12
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Human evolution – hominin skulls, skeletons, stone tools and out of Africa
Biology · Evolution
Compare schematic skulls, pelvises and femurs of a chimpanzee and fossil hominins up to Homo sapiens: brain volume,...
Ages 17–18
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Genetic drift – Wright–Fisher model, bottleneck and founder effect
Biology · Evolution
Several populations of the same size N start with the same frequency p₀ of allele A; each generation, the 2N alleles...
Ages 17–18
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Endler's Guppies – Natural and Sexual Selection on Colour Spots
Biology · Evolution
Set the predators and the strength of female preference in a guppy pool and follow the number and length of the...
Ages 17–18
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Pollination and coevolution – flowers and pollinators, courtship and evolutionary arms races
Biology · Evolution
Four screens on reproductive success: design a flower (colour, scent, nectar, corolla tube, opening time,...
Ages 16–17
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Extinction and environmental change – adapt, shift range or die out; mass extinctions
Biology · Evolution
Six species sharing a landscape face climate warming, habitat loss or a sudden catastrophe. Set the rate of change...
Ages 17–18
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Sealed Jar Mesocosm – Ecosystem Stability Lab
Biology · Ecology & Environment
Set up a sealed jar with water, plants, snails and pond mud, choose the hours of light and the added nitrate, and...
Ages 17–18
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Nitrogen cycle – fixation, nitrification, denitrification and eutrophication
Biology · Ecology & Environment
A box model of the nitrogen cycle in the soil of a grazed meadow: N₂ fixation by Rhizobium in legume root nodules,...
Ages 17–18
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Biology in action – molecular biology, biological control, and human ecology
Biology · Ecology & Environment
Three biology topics in one simulation, selected with the topic parameter. Molecular biology: run a PCR reaction...
Ages 17–18
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Sustainable fishing – maximum sustainable yield and the tragedy of the commons
Biology · Ecology & Environment
A fish stock with logistic growth is shared by several fishers. Choose your number of boats, the management regime...
Ages 17–18
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Ecological succession – primary, secondary and the plagioclimax
Biology · Ecology & Environment
Fast-forward hundreds of years on bare rock, ground left by a retreating glacier, a coastal sand dune, an abandoned...
Ages 17–18
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Wallace's Line – Biodiversity of Indonesia
Biology · Ecology & Environment
A map of Indonesia with Wallace's, Weber's and Lydekker's lines. Sort 16 real species (orangutan, Rafflesia, anoa,...
Ages 17–18
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Tolerance curves – abiotic factors, limiting factors and zonation
Biology · Ecology & Environment
Move sliders for temperature, light, soil water (or salinity) and pH to see that every species has its own range of...
Ages 17–18
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Biological pest control – natural enemies versus chemical pesticides
Biology · Ecology & Environment
Simulate one rice-growing season with a brown planthopper population and its natural enemies (mirid bugs, spiders)....
Ages 17–18
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Ecosystems of Ecuador – A Transect from the Galápagos to the Amazon
Biology · Ecology & Environment
Move along a transect across Ecuador, from the Galápagos and the Pacific coast over the Andes to the Amazon, and...
Ages 17–18
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Energy budget lab: from plant to caterpillar
Biology · Ecology & Environment
A virtual lab after AP Biology Investigation 10: weigh brussels sprouts and cabbage white caterpillars before and...
Ages 17–18
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Decay – lipase and milk practical, compost heap and biogas digester
Biology · Ecology & Environment
Three screens on decomposers. Lipase practical: milk, sodium carbonate solution and phenolphthalein are pink; add...
Ages 15–16
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Eutrophication and water pollution – lake, catchment and indicator species
Biology · Ecology & Environment
A lake and its catchment: add fertiliser runoff from farmland, sewage from a town, copper from a mine or acid rain,...
Ages 17–18
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Species interactions – competition, predation, parasitism and mutualism (Lotka–Volterra)
Biology · Ecology & Environment
Two species with six switchable interactions: Lotka–Volterra competition dN₁/dt = r₁N₁(K₁ − N₁ − α₁₂N₂)/K₁,...
Ages 17–18
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Biodiversity conservation planner – reserves, wildlife corridors and invasive species
Biology · Ecology & Environment
A landscape of forest patches and farmland with 11 species. On a limited budget, place nature reserves, plant...
Ages 17–18
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Group living and optimal foraging – costs and benefits of behaviour
Biology · Ecology & Environment
An agent model of a fish school, a bird flock and a zebra herd under attack: set the group size and cohesion, then...
Ages 17–18
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Food chains, energy pyramids and the carbon cycle
Biology · Ecology & Environment
Solar energy fixed by producers is passed along a food chain through successive trophic levels; at each level most...
Ages 17–18
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Adaptations explorer – deserts, polar regions, water and extremophiles
Biology · Ecology & Environment
Pick a habitat (hot desert, polar ice, rainforest, lake, sea, deep sea, hot spring, salt lake) and an organism, tick...
Ages 17–18
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Bioaccumulation and biomagnification – DDT, mercury and microplastics in a food chain
Biology · Ecology & Environment
An aquatic food chain from plankton through small fish and large fish to a fish-eating bird takes up a persistent...
Ages 17–18
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Predator–prey dynamics – rabbits and foxes
Biology · Ecology & Environment
The rabbit population grows logistically, dN/dt = rN(1 − N/K), heading toward the environment's carrying capacity K;...
Ages 17–18
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Teaching guides for Biology
All guides- Biotech Virtual Lab: Transformation and Gel ElectrophoresisBiotech virtual lab: transform E. coli with a GFP plasmid, calculate transformation efficiency, then cut DNA and size the fragments on an agarose gel.
- Hardy–Weinberg Virtual Lab: Selection and Genetic DriftHardy–Weinberg virtual lab: model allele frequencies over many generations, calculate p², 2pq and q², then break the rules with selection and drift.
- Mitotic Index Virtual Lab: Root Tip Squash and Chi-SquaredA mitotic index virtual lab: squash onion root tips, classify cells by stage, compare regions and lectin with chi-squared, and estimate how long prophase lasts.
- Pollination Virtual Lab: Flower Tubes, Pollinators and SeedsA pollination virtual lab: lengthen a flower's corolla tube, count bee, butterfly and hummingbird visits, measure seed set and explain flower–pollinator fit.
- Respirometer Virtual Lab: Oxygen Uptake by Germinating PeasRespirometer virtual lab: measure O₂ uptake by germinating and dry peas, correct with a glass-bead tube, find the rate at each temperature and calculate Q10.
- Selective Breeding Virtual Lab: Artificial SelectionA selective breeding virtual lab: choose the hairiest Fast Plants as parents, measure S and R, calculate realized heritability and watch inbreeding rise.